Charlton manager Phil Parkinson will change a winning team, with new recruits Simon Francis and Lee Martin poised to start.
Midfielder Jose Semedo was sent off during the opening-day win at Bournemouth, although Charlton have appealed against the decision.
MATCH FACTS
Head-to-head
• Shrewsbury and Charlton have never met in a cup competition before.
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• The Addicks have only won once at Shrewsbury - a 2-0 victory in the old Third Division in December 1972.
Shrewsbury
• Shrewsbury are hoping to avoid going out in the first round for the fourth time in five years, and the third season in a row.
• The 1961 semi-finalists shared six goals with Ipswich at this stage last season, before losing on penalties.
Charlton
• Charlton have not won or scored in this competition for three years.
• Since achieving a quarter-final berth in 2007, Charlton have fallen foul of lower-division clubs. Defeat here would see them going out to a League Two side for the second season in a row.
Source: BBC Sport
Source: BBC Sport